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Shocking New ApoE4 Science About Estrogen and Brain Health!

Normal cholesterol levels don’t mean your brain is safe—especially if you’re a woman with ApoE4.

4 min read
Shocking New ApoE4 Science About Estrogen and Brain Health!
Evidence-Backed

Shocking New ApoE4 Science About Estrogen and Brain Health!

Normal cholesterol levels don’t mean your brain is safe—especially if you’re a woman with ApoE4.

Normal cholesterol levels don’t mean your brain is safe—especially if you’re a woman with ApoE4.

In this episode, I break down groundbreaking research from the Alzheimer’s Association International Conference on APOE & Lipid Biology (March 2025).

I reveal how female ApoE4 carriers develop cholesterol buildup in brain cells long before cognitive symptoms appear.

You'll learn:

  • Why standard blood tests can miss early brain dysfunction

  • How cholesterol gets trapped in endosomes and mitochondria in female APOE4 brains

  • What this tells us about sex-specific Alzheimer’s risk (and how to intervene early)

This video is for ApoE4 carriers (especially women in midlife) who want to understand their unique risks and take evidence-based steps to reduce them.

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Written by

Phoenix Team

Phoenix Team is a contributor to the APOE4 Blog, sharing evidence-based insights for the APOE4 community.

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