Phoenix friends,

This was the main presentation at the AAIC 2025, the Welcome Award presentation.
It comes with some bad news for many of us, but also a lot of hope.

The Bad News First:

- In her study, 100% of patient testing positive for amyloid AND tau develop cognitive impairment issues within 6 years

- By age 70: 50% of E4/E3 carriers and 90% of E4/E4 carriers have brain amyloid

- Women face double vulnerability with inflammation markers

But Here's What Changes Everything:

✅ We have a 15-20 YEAR window to act before symptoms

✅ 45% of our risk is CONTROLLABLE through lifestyle

The Surprises:

• Mindfulness is the TOP protective factor (not just exercise!)

• Full list of protective factors in the video

• Blood pressure meds protect the brain from amyloid

• Education delays pathology even with genetic mutations

• New DORA sleep drugs change brain proteins in just 36 hours

And quoting Dr. Villeneuve's directly:

"An increased effort needs to be devoted toward finding treatment for APOE4 carriers"

Finally, researchers are calling for treatments designed specifically for US, not generic approaches.

I break down all the conference learnings here:

TAKE ACTION:

Join the Phoenix Community to beat the odds and outsmart Alzheimer's → 

Credits: Alzheimer's Association International Conference 2025 Sylvia Villeneuve (McGill University, Canada)

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How boring…
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