APOE4 and brain stress: why your hs-CRP, ferritin, and iron need a different lens
Originally published on YouTube on 15 June 2026.
Original video: https://www.youtube.com/watch?v=TFQ-pN0OqOM
Your hs-CRP looks normal. What does that mean through an APOE4 lens?
In Part 2 of our biomarker series, I sit down with Dr. Grant Fraser to discuss inflammation, iron, ferritin and GGT, including which tests he uses, how he reads them and how to avoid unnecessary testing.
RESOURCES
Apply to join Phoenix: https://apoe4.link/Inflammation
APOE4 Inflammation, Gut & Stress Guide: https://apoe4.link/InflammationG
Weekly Newsletter: https://apoe4.link/InflammationN
APOE4 Blood Work Blueprint: https://apoe4.link/InflammationB
CHAPTERS
00:00 Introduction
01:14 Episode Overview
02:27 hs-CRP & What It Actually Means for ApoE4 Carriers
06:09 How to Lower CRP (Supplements & Lifestyle)
10:46 Fiber Intake Warning When Changing Diet
12:04 Why Iron & Ferritin Matter More Than You Think for ApoE4
19:00 Should You Test IL-6, TNF-Alpha & Other Cytokines?
21:40 GGT as an Oxidative Stress Signal
22:54 Inflammation Testing Summary (What to Run & How Often)
27:01 The Rule That Saves You From Wasting Money on Tests
31:00 Pre-MAS Cognitive Test
32:29 What's Coming in Phoenix